Neutropenic sepsis is a significant infection following immunosuppression due to a low neutrophil count.
It is a common and predictable complication of bone marrow disorders and anticancer treatments, particularly chemotherapy.
The estimated incidence is 70-100% during the neutropenic phase after intensive cytotoxic therapy.
Neutropenic sepsis is a time-critical oncological emergency.
It is the leading cause of non-relapse related mortality in patients with cancer undergoing intensive chemotherapy.
The risk of life-threatening infection is related to the degree of immunosuppression, as indicated by the neutrophil count.
Optimising diagnosis and management of neutropenic sepsis can improve outcomes and reduce mortality for patients undergoing cytotoxic cancer therapies.
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At the end of this module participants will be able to:
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